Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells

Lin28 acts as a repressor of microRNA processing and as a post-transcriptional regulatory factor for a subset of mRNAs. Here we report that in human embryonic stem cells Lin28 facilitates the expression of the pivotal pluripotency factor Oct4 at the post-transcriptional level. We provide evidence th...

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Detalles Bibliográficos
Autores principales: Qiu, Caihong, Ma, Yinghong, Wang, Jianquan, Peng, Shuping, Huang, Yingqun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831306/
https://www.ncbi.nlm.nih.gov/pubmed/19966271
http://dx.doi.org/10.1093/nar/gkp1071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831306/
https://www.ncbi.nlm.nih.gov/pubmed/19966271
http://dx.doi.org/10.1093/nar/gkp1071

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