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Analysis of differential DNA damage in the mitochondrial genome employing a semi-long run real-time PCR approach
The maintenance of the mitochondrial genomic integrity is a prerequisite for proper mitochondrial function. Due to the high concentration of reactive oxygen species (ROS) generated by the oxidative phosphorylation pathway, the mitochondrial genome is highly exposed to oxidative stress leading to mit...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831309/ https://www.ncbi.nlm.nih.gov/pubmed/19966269 http://dx.doi.org/10.1093/nar/gkp1082 |