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Analysis of differential DNA damage in the mitochondrial genome employing a semi-long run real-time PCR approach

The maintenance of the mitochondrial genomic integrity is a prerequisite for proper mitochondrial function. Due to the high concentration of reactive oxygen species (ROS) generated by the oxidative phosphorylation pathway, the mitochondrial genome is highly exposed to oxidative stress leading to mit...

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Detalles Bibliográficos
Autores principales:	Rothfuss, Oliver, Gasser, Thomas, Patenge, Nadja
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831309/ https://www.ncbi.nlm.nih.gov/pubmed/19966269 http://dx.doi.org/10.1093/nar/gkp1082

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