Cargando…

The transcriptional transactivator Tat selectively regulates viral splicing

HIV-1 gene expression requires both viral and cellular factors to control and coordinate transcription. While the viral factor Tat is known for its transcriptional transactivator properties, we present evidence for an unexpected function of Tat in viral splicing regulation. We used a series of HIV-1...

Descripción completa

Detalles Bibliográficos
Autores principales: Jablonski, Joseph A., Amelio, Antonio L., Giacca, Mauro, Caputi, Massimo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831323/
https://www.ncbi.nlm.nih.gov/pubmed/19966273
http://dx.doi.org/10.1093/nar/gkp1105