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A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA
Genomic RNA of primate lentiviruses serves both as an mRNA that encodes Gag and Gag-Pol polyproteins and as a propagated genome. Translation of this RNA is initiated by standard cap dependant mechanism or by internal entry of the ribosome. Two regions of the genomic RNA are able to attract initiatio...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831325/ https://www.ncbi.nlm.nih.gov/pubmed/19969542 http://dx.doi.org/10.1093/nar/gkp1109 |