Optimization of the BLASTN substitution matrix for prediction of non-specific DNA microarray hybridization

DNA microarray measurements are susceptible to error caused by non-specific hybridization between a probe and a target (cross-hybridization), or between two targets (bulk-hybridization). Search algorithms such as BLASTN can quickly identify potentially hybridizing sequences. We set out to improve BL...

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Detalles Bibliográficos
Autores principales: Eklund, Aron C., Friis, Pia, Wernersson, Rasmus, Szallasi, Zoltan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831327/
https://www.ncbi.nlm.nih.gov/pubmed/19969549
http://dx.doi.org/10.1093/nar/gkp1116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831327/
https://www.ncbi.nlm.nih.gov/pubmed/19969549
http://dx.doi.org/10.1093/nar/gkp1116

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