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Optimization of the BLASTN substitution matrix for prediction of non-specific DNA microarray hybridization
DNA microarray measurements are susceptible to error caused by non-specific hybridization between a probe and a target (cross-hybridization), or between two targets (bulk-hybridization). Search algorithms such as BLASTN can quickly identify potentially hybridizing sequences. We set out to improve BL...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831327/ https://www.ncbi.nlm.nih.gov/pubmed/19969549 http://dx.doi.org/10.1093/nar/gkp1116 |