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Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase

RNA helicases function in numerous aspects of RNA biology. These enzymes are RNA-stimulated ATPases that translocate on RNA and unwind or remodel structured RNA in an ATP-dependent fashion. How ATP and the ATPase cycle fuel the work performed by helicases is not completely clear. The hepatitis C vir...

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Detalles Bibliográficos
Autores principales: Wang, Qixin, Arnold, Jamie J., Uchida, Akira, Raney, Kevin D., Cameron, Craig E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831328/
https://www.ncbi.nlm.nih.gov/pubmed/19969541
http://dx.doi.org/10.1093/nar/gkp1118