Bone marrow adipocytes as negative regulators of the hematopoietic microenvironment

Osteoblasts and endothelium constitute functional niches that support hematopoietic stem cells (HSC) in mammalian bone marrow (BM) 1,2,3 . Adult BM also contains adipocytes, whose numbers correlate inversely with the hematopoietic activity of the marrow. Fatty infiltration of hematopoietic red marro...

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Detalles Bibliográficos
Autores principales: Naveiras, Olaia, Nardi, Valentina, Wenzel, Pamela L., Fahey, Frederic, Daley, George Q.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831539/
https://www.ncbi.nlm.nih.gov/pubmed/19516257
http://dx.doi.org/10.1038/nature08099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831539/
https://www.ncbi.nlm.nih.gov/pubmed/19516257
http://dx.doi.org/10.1038/nature08099

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