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Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept

BACKGROUND: Alefacept treatment is highly effective in a select group patients with moderate-to-severe psoriasis, and is an ideal candidate to develop systems to predict who will respond to therapy. A clinical trial of 22 patients with moderate to severe psoriasis treated with alefacept was conducte...

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Detalles Bibliográficos
Autores principales: Suárez-Fariñas, Mayte, Shah, Kejal R, Haider, Asifa S, Krueger, James G, Lowes, Michelle A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831811/
https://www.ncbi.nlm.nih.gov/pubmed/20152045
http://dx.doi.org/10.1186/1471-5945-10-1