COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke

BACKGROUND: Anticoagulation is an important means to prevent from acute ischemic stroke but is associated with a significant risk of severe hemorrhages. Previous studies have shown that blood coagulation factor XII (FXII)-deficient mice are protected from pathological thrombus formation during cereb...

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Detalles Bibliográficos
Autores principales: Kraft, Peter, Schwarz, Tobias, Pochet, Lionel, Stoll, Guido, Kleinschnitz, Christoph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831840/
https://www.ncbi.nlm.nih.gov/pubmed/20298537
http://dx.doi.org/10.1186/2040-7378-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831840/
https://www.ncbi.nlm.nih.gov/pubmed/20298537
http://dx.doi.org/10.1186/2040-7378-2-5

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