Cargando…

Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs

BACKGROUND: Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2)-mediated survival signaling is critical to endothelial cell survival, maintenance of the vasculature and alveolar structure and regeneration of lung tissue. Reduced VEGF and VEGFR2 expression in emphysematous lungs ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Marwick, John A, Edirisinghe, Indika, Arunachalam, Gnanapragasam, Stevenson, Christopher S, MacNee, William, Kirkham, Paul A, Rahman, Irfan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831890/
https://www.ncbi.nlm.nih.gov/pubmed/20205917
http://dx.doi.org/10.1186/1476-9255-7-11