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GSK3 and p53 - is there a link in Alzheimer's disease?

BACKGROUND: Recent evidence suggests that glycogen synthase kinase-3β (GSK3β) is implicated in both sporadic and familial forms of Alzheimer's disease. The transcription factor, p53 also plays a role and has been linked to an increase in tau hyperphosphorylation although the effect is indirect....

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Detalles Bibliográficos
Autores principales: Proctor, Carole J, Gray, Douglas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831894/
https://www.ncbi.nlm.nih.gov/pubmed/20181016
http://dx.doi.org/10.1186/1750-1326-5-7