Arsenic Exposure Transforms Human Epithelial Stem/Progenitor Cells into a Cancer Stem-like Phenotype

BACKGROUND: Inorganic arsenic is a ubiquitous environmental carcinogen affecting millions of people worldwide. Evolving theory predicts that normal stem cells (NSCs) are transformed into cancer stem cells (CSCs) that then drive oncogenesis. In humans, arsenic is carcinogenic in the urogenital system...

Descripción completa

Detalles Bibliográficos
Autores principales: Tokar, Erik J., Diwan, Bhalchandra A., Waalkes, Michael P.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831952/
https://www.ncbi.nlm.nih.gov/pubmed/20056578
http://dx.doi.org/10.1289/ehp.0901059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831952/
https://www.ncbi.nlm.nih.gov/pubmed/20056578
http://dx.doi.org/10.1289/ehp.0901059

Ejemplares similares