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The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension

BACKGROUND: Pulmonary vascular diseases are increasingly recognised as important clinical conditions. Pulmonary hypertension associated with a range of aetiologies is difficult to treat and associated with progressive morbidity and mortality. Current therapies for pulmonary hypertension include phos...

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Detalles Bibliográficos
Autores principales: Harrington, Louise S., Moreno, Laura, Reed, Anna, Wort, Stephen J., Desvergne, Béatrice, Garland, Christopher, Zhao, Lan, Mitchell, Jane A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831997/
https://www.ncbi.nlm.nih.gov/pubmed/20209098
http://dx.doi.org/10.1371/journal.pone.0009526