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The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension
BACKGROUND: Pulmonary vascular diseases are increasingly recognised as important clinical conditions. Pulmonary hypertension associated with a range of aetiologies is difficult to treat and associated with progressive morbidity and mortality. Current therapies for pulmonary hypertension include phos...
Autores principales: | Harrington, Louise S., Moreno, Laura, Reed, Anna, Wort, Stephen J., Desvergne, Béatrice, Garland, Christopher, Zhao, Lan, Mitchell, Jane A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831997/ https://www.ncbi.nlm.nih.gov/pubmed/20209098 http://dx.doi.org/10.1371/journal.pone.0009526 |
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