In Vitro Metabolic and Mitogenic Signaling of Insulin Glargine and Its Metabolites

BACKGROUND: Insulin glargine (Lantus®) is a long-acting basal insulin analog that demonstrates effective day-long glycemic control and a lower incidence of hypoglycemia than NPH insulin. After subcutaneous injection insulin glargine is partly converted into the two main metabolites M1 ([Gly(A21)]ins...

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Detalles Bibliográficos
Autores principales: Sommerfeld, Mark R., Müller, Günter, Tschank, Georg, Seipke, Gerhard, Habermann, Paul, Kurrle, Roland, Tennagels, Norbert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832019/
https://www.ncbi.nlm.nih.gov/pubmed/20209060
http://dx.doi.org/10.1371/journal.pone.0009540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832019/
https://www.ncbi.nlm.nih.gov/pubmed/20209060
http://dx.doi.org/10.1371/journal.pone.0009540

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