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In Vitro Metabolic and Mitogenic Signaling of Insulin Glargine and Its Metabolites
BACKGROUND: Insulin glargine (Lantus®) is a long-acting basal insulin analog that demonstrates effective day-long glycemic control and a lower incidence of hypoglycemia than NPH insulin. After subcutaneous injection insulin glargine is partly converted into the two main metabolites M1 ([Gly(A21)]ins...
Autores principales: | Sommerfeld, Mark R., Müller, Günter, Tschank, Georg, Seipke, Gerhard, Habermann, Paul, Kurrle, Roland, Tennagels, Norbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832019/ https://www.ncbi.nlm.nih.gov/pubmed/20209060 http://dx.doi.org/10.1371/journal.pone.0009540 |
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