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Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice

BACKGROUND: Chronic inflammation is a characteristic feature of diabetic cutaneous wounds. We sought to delineate novel mechanisms involved in the impairment of resolution of inflammation in diabetic cutaneous wounds. At the wound-site, efficient dead cell clearance (efferocytosis) is a pre-requisit...

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Detalles Bibliográficos
Autores principales: Khanna, Savita, Biswas, Sabyasachi, Shang, Yingli, Collard, Eric, Azad, Ali, Kauh, Courtney, Bhasker, Vineet, Gordillo, Gayle M., Sen, Chandan K., Roy, Sashwati
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832020/
https://www.ncbi.nlm.nih.gov/pubmed/20209061
http://dx.doi.org/10.1371/journal.pone.0009539