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Parkin-mediated ubiquitination regulates phospholipase C-γ1

Mutations in parkin cause autosomal recessive forms of Parkinson’s disease (PD), with an early age of onset and similar pathological phenotype to the idiopathic disease. Parkin has been identified as an E3 ubiquitin ligase that mediates different types of ubiquitination, which has made the search fo...

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Detalles Bibliográficos
Autores principales: Dehvari, Nodi, Sandebring, Anna, Flores-Morales, Amilcar, Mateos, Laura, Chuan, Yin-Choy, Goldberg, Matthew S, Cookson, Mark R, Cowburn, Richard F, Cedazo-Mínguez, Angel
Formato: Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832102/
https://www.ncbi.nlm.nih.gov/pubmed/18671761
http://dx.doi.org/10.1111/j.1582-4934.2008.00443.x