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Diversity of protein structures and difficulties in fold recognition: the curious case of protein G
We examine the ability of current state-of-the-art methods in protein structure prediction to discriminate topologically distant folds encoded by highly similar (>90% sequence identity) designed proteins in blind protein structure prediction experiments. We detail the corresponding prognosis for...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Biology Reports Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832337/ https://www.ncbi.nlm.nih.gov/pubmed/20209018 http://dx.doi.org/10.3410/B1-69 |