Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

Epidemiological studies showed that high levels of oxidized low-density lipoproteins (oxLDLs) are associated with increased cancer risk. We examined the direct effect of physiologic concentrations oxLDL on cancer cells. OxLDLs were cytotoxic and activate both apoptosis and autophagy. OxLDLs have lig...

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Detalles Bibliográficos
Autores principales: Zabirnyk, Olga, Liu, Wei, Khalil, Shadi, Sharma, Anit, Phang, James M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832543/
https://www.ncbi.nlm.nih.gov/pubmed/19942609
http://dx.doi.org/10.1093/carcin/bgp299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832543/
https://www.ncbi.nlm.nih.gov/pubmed/19942609
http://dx.doi.org/10.1093/carcin/bgp299

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