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Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy
Epidemiological studies showed that high levels of oxidized low-density lipoproteins (oxLDLs) are associated with increased cancer risk. We examined the direct effect of physiologic concentrations oxLDL on cancer cells. OxLDLs were cytotoxic and activate both apoptosis and autophagy. OxLDLs have lig...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832543/ https://www.ncbi.nlm.nih.gov/pubmed/19942609 http://dx.doi.org/10.1093/carcin/bgp299 |