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Hypervariable intronic region in NCX1 is enriched in short insertion-deletion polymorphisms and showed association with cardiovascular traits
BACKGROUND: Conserved non-coding regions (CNR) have been shown to harbor gene expression regulatory elements. Genetic variations in these regions may potentially contribute to complex disease susceptibility. METHODS: We targeted CNRs of cardiovascular disease (CVD) candidate gene, Na(+)-Ca(2+) excha...
Autores principales: | Kepp, Katrin, Org, Elin, Sõber, Siim, Kelgo, Piret, Viigimaa, Margus, Veldre, Gudrun, Tõnisson, Neeme, Juhanson, Peeter, Putku, Margus, Kindmark, Andreas, Kožich, Viktor, Laan, Maris |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832636/ https://www.ncbi.nlm.nih.gov/pubmed/20109173 http://dx.doi.org/10.1186/1471-2350-11-15 |
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