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Parameter Estimation and Model Selection in Computational Biology
A central challenge in computational modeling of biological systems is the determination of the model parameters. Typically, only a fraction of the parameters (such as kinetic rate constants) are experimentally measured, while the rest are often fitted. The fitting process is usually based on experi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832681/ https://www.ncbi.nlm.nih.gov/pubmed/20221262 http://dx.doi.org/10.1371/journal.pcbi.1000696 |