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CASPASE 2-MEDIATED TUMOR SUPPRESSION INVOLVES SURVIVIN GENE SILENCING

One of the pivotal functions of endogenous tumor suppression is to oppose aberrant cell survival, but the molecular requirements of this process are not completely understood. Here, we show that caspase 2, a death effector with largely unknown functions, represses transcription of the survivin gene,...

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Detalles Bibliográficos
Autores principales: Guha, Minakshi, Xia, Fang, Raskett, Christopher M., Altieri, Dario C.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832727/
https://www.ncbi.nlm.nih.gov/pubmed/19935698
http://dx.doi.org/10.1038/onc.2009.428