Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling

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The EphA4 tyrosine kinase cell surface receptor regulates an array of physiological processes and is the only currently known class A Eph receptor that binds both A and B class ephrins with high affinity. We have solved the crystal structure of the EphA4 ligand binding domain alone and in complex wi...

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Detalles Bibliográficos
Autores principales: Bowden, Thomas A., Aricescu, A. Radu, Nettleship, Joanne E., Siebold, Christian, Rahman-Huq, Nahid, Owens, Raymond J., Stuart, David I., Jones, E. Yvonne
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832735/
https://www.ncbi.nlm.nih.gov/pubmed/19836338
http://dx.doi.org/10.1016/j.str.2009.07.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832735/
https://www.ncbi.nlm.nih.gov/pubmed/19836338
http://dx.doi.org/10.1016/j.str.2009.07.018

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