Cargando…
Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling
The EphA4 tyrosine kinase cell surface receptor regulates an array of physiological processes and is the only currently known class A Eph receptor that binds both A and B class ephrins with high affinity. We have solved the crystal structure of the EphA4 ligand binding domain alone and in complex wi...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832735/ https://www.ncbi.nlm.nih.gov/pubmed/19836338 http://dx.doi.org/10.1016/j.str.2009.07.018 |