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Endocytosis of the Anthrax Toxin Is Mediated by Clathrin, Actin and Unconventional Adaptors

The anthrax toxin is a tripartite toxin, where the two enzymatic subunits require the third subunit, the protective antigen (PA), to interact with cells and be escorted to their cytoplasmic targets. PA binds to cells via one of two receptors, TEM8 and CMG2. Interestingly, the toxin times and trigger...

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Detalles Bibliográficos
Autores principales: Abrami, Laurence, Bischofberger, Mirko, Kunz, Béatrice, Groux, Romain, van der Goot, F. Gisou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832758/
https://www.ncbi.nlm.nih.gov/pubmed/20221438
http://dx.doi.org/10.1371/journal.ppat.1000792