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Endocytosis of the Anthrax Toxin Is Mediated by Clathrin, Actin and Unconventional Adaptors
The anthrax toxin is a tripartite toxin, where the two enzymatic subunits require the third subunit, the protective antigen (PA), to interact with cells and be escorted to their cytoplasmic targets. PA binds to cells via one of two receptors, TEM8 and CMG2. Interestingly, the toxin times and trigger...
Autores principales: | Abrami, Laurence, Bischofberger, Mirko, Kunz, Béatrice, Groux, Romain, van der Goot, F. Gisou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832758/ https://www.ncbi.nlm.nih.gov/pubmed/20221438 http://dx.doi.org/10.1371/journal.ppat.1000792 |
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