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α- and β-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy

Adducins are cytoskeletal actin-binding proteins (α, β, γ) that function as heterodimers and heterotetramers and are encoded by distinct genes. Experimental and clinical evidence implicates α- and β-adducin variants in hypertension and renal dysfunction. Here, we have addressed the role of α- and β-...

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Detalles Bibliográficos
Autores principales: Ferrandi, Mara, Cusi, Daniele, Molinari, Isabella, Del Vecchio, Lucia, Barlassina, Cristina, Rastaldi, Maria Pia, Schena, Francesco Paolo, Macciardi, Fabio, Marcantoni, Carmelita, Roccatello, Dario, Peters, Luanne L., Armelloni, Silvia, Min, Li, Giardino, Laura, Mattinzoli, Deborah, Camisasca, Claudio, Palazzo, Fiorentina, Manunta, Paolo, Ferrari, Patrizia, Bianchi, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832889/
https://www.ncbi.nlm.nih.gov/pubmed/19838659
http://dx.doi.org/10.1007/s00109-009-0549-x