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Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4

BACKGROUND: B. burgdorferi sensu lato (sl) is the etiological agent of Lyme borreliosis in humans. Spirochetes have adapted themselves to the human immune system in many distinct ways. One important immune escape mechanism for evading complement activation is the binding of complement regulators Fac...

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Detalles Bibliográficos
Autores principales: van Burgel, Nathalie D, Kraiczy, Peter, Schuijt, Tim J, Zipfel, Peter F, van Dam, Alje P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833144/
https://www.ncbi.nlm.nih.gov/pubmed/20146822
http://dx.doi.org/10.1186/1471-2180-10-43