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Computational prediction and experimental validation of evolutionarily conserved microRNA target genes in bilaterian animals
BACKGROUND: In many eukaryotes, microRNAs (miRNAs) bind to complementary sites in the 3'-untranslated regions (3'-UTRs) of target messenger RNAs (mRNAs) and regulate their expression at the stage of translation. Recent studies have revealed that many miRNAs are evolutionarily conserved; ho...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833159/ https://www.ncbi.nlm.nih.gov/pubmed/20144220 http://dx.doi.org/10.1186/1471-2164-11-101 |