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Computational prediction and experimental validation of evolutionarily conserved microRNA target genes in bilaterian animals

BACKGROUND: In many eukaryotes, microRNAs (miRNAs) bind to complementary sites in the 3'-untranslated regions (3'-UTRs) of target messenger RNAs (mRNAs) and regulate their expression at the stage of translation. Recent studies have revealed that many miRNAs are evolutionarily conserved; ho...

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Detalles Bibliográficos
Autores principales:	Takane, Kahori, Fujishima, Kosuke, Watanabe, Yuka, Sato, Asako, Saito, Nobuto, Tomita, Masaru, Kanai, Akio
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833159/ https://www.ncbi.nlm.nih.gov/pubmed/20144220 http://dx.doi.org/10.1186/1471-2164-11-101

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