Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

BACKGROUND: The clinical utility for mefloquine has been eroded due to its association with adverse neurological effects. Better-tolerated alternatives are required. The objective of the present study was the identification of lead compounds that are as effective as mefloquine, but exhibit physioche...

Descripción completa

Detalles Bibliográficos
Autores principales: Milner, Erin, McCalmont, William, Bhonsle, Jayendra, Caridha, Diana, Cobar, Jose, Gardner, Sean, Gerena, Lucia, Goodine, Duane, Lanteri, Charlotte, Melendez, Victor, Roncal, Norma, Sousa, Jason, Wipf, Peter, Dow, Geoffrey Stuart
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833169/
https://www.ncbi.nlm.nih.gov/pubmed/20149249
http://dx.doi.org/10.1186/1475-2875-9-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833169/
https://www.ncbi.nlm.nih.gov/pubmed/20149249
http://dx.doi.org/10.1186/1475-2875-9-51

Ejemplares similares