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Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols

BACKGROUND: The clinical utility for mefloquine has been eroded due to its association with adverse neurological effects. Better-tolerated alternatives are required. The objective of the present study was the identification of lead compounds that are as effective as mefloquine, but exhibit physioche...

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Detalles Bibliográficos
Autores principales:	Milner, Erin, McCalmont, William, Bhonsle, Jayendra, Caridha, Diana, Cobar, Jose, Gardner, Sean, Gerena, Lucia, Goodine, Duane, Lanteri, Charlotte, Melendez, Victor, Roncal, Norma, Sousa, Jason, Wipf, Peter, Dow, Geoffrey Stuart
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833169/ https://www.ncbi.nlm.nih.gov/pubmed/20149249 http://dx.doi.org/10.1186/1475-2875-9-51

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