Silencing of Ribosomal Protein S9 Elicits a Multitude of Cellular Responses Inhibiting the Growth of Cancer Cells Subsequent to p53 Activation

BACKGROUND: Disruption of the nucleolus often leads to activation of the p53 tumor suppressor pathway through inhibition of MDM2 that is mediated by a limited set of ribosomal proteins including RPL11 and RPL5. The effects of ribosomal protein loss in cultured mammalian cells have not been thoroughl...

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Detalles Bibliográficos
Autores principales: Lindström, Mikael S., Nistér, Monica
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833189/
https://www.ncbi.nlm.nih.gov/pubmed/20221446
http://dx.doi.org/10.1371/journal.pone.0009578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833189/
https://www.ncbi.nlm.nih.gov/pubmed/20221446
http://dx.doi.org/10.1371/journal.pone.0009578

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