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Identifying Unexpected Therapeutic Targets via Chemical-Protein Interactome

Drug medications inevitably affect not only their intended protein targets but also other proteins as well. In this study we examined the hypothesis that drugs that share the same therapeutic effect also share a common therapeutic mechanism by targeting not only known drug targets, but also by inter...

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Detalles Bibliográficos
Autores principales: Yang, Lun, Chen, Jian, Shi, Leming, Hudock, Michael P., Wang, Kejian, He, Lin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833192/
https://www.ncbi.nlm.nih.gov/pubmed/20221449
http://dx.doi.org/10.1371/journal.pone.0009568