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Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation

The biological mode of action of artemisinin, a potent antimalarial, has long been controversial. Previously we established a yeast model addressing its mechanism of action and found mitochondria the key in executing artemisinin's action. Here we present data showing that artemisinin directly a...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Huang, Liying, Li, Jian, Fan, Qiangwang, Long, Yicheng, Li, Ying, Zhou, Bing
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833198/
https://www.ncbi.nlm.nih.gov/pubmed/20221395
http://dx.doi.org/10.1371/journal.pone.0009582