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Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation
The biological mode of action of artemisinin, a potent antimalarial, has long been controversial. Previously we established a yeast model addressing its mechanism of action and found mitochondria the key in executing artemisinin's action. Here we present data showing that artemisinin directly a...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833198/ https://www.ncbi.nlm.nih.gov/pubmed/20221395 http://dx.doi.org/10.1371/journal.pone.0009582 |