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Shigella Mediated Depletion of Macrophages in a Murine Breast Cancer Model Is Associated with Tumor Regression

A tumor promoting role of macrophages has been described for a transgenic murine breast cancer model. In this model tumor-associated macrophages (TAMs) represent a major component of the leukocytic infiltrate and are associated with tumor progression. Shigella flexneri is a bacterial pathogen known...

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Detalles Bibliográficos
Autores principales: Galmbacher, Katharina, Heisig, Martin, Hotz, Christian, Wischhusen, Joerg, Galmiche, Antoine, Bergmann, Birgit, Gentschev, Ivaylo, Goebel, Werner, Rapp, Ulf R., Fensterle, Joachim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833200/
https://www.ncbi.nlm.nih.gov/pubmed/20221397
http://dx.doi.org/10.1371/journal.pone.0009572