MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducers

BACKGROUND: We recently identified matrix extracellular phosphoglycoprotein/osteoblast factor 45 (MEPE/OF45) as a new cofactor of CHK1 in rat cells. The aim of this study was to determine the role of human MEPE/OF45 (hMEPE/OF45 has ∼50% homology with rat MEPE/OF45 (rMEPE/OF45)) in affecting the sens...

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Detalles Bibliográficos
Autores principales: Zhang, P, Wang, H, Rowe, P S N, Hu, B, Wang, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833259/
https://www.ncbi.nlm.nih.gov/pubmed/20145617
http://dx.doi.org/10.1038/sj.bjc.6605572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833259/
https://www.ncbi.nlm.nih.gov/pubmed/20145617
http://dx.doi.org/10.1038/sj.bjc.6605572

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