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MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducers
BACKGROUND: We recently identified matrix extracellular phosphoglycoprotein/osteoblast factor 45 (MEPE/OF45) as a new cofactor of CHK1 in rat cells. The aim of this study was to determine the role of human MEPE/OF45 (hMEPE/OF45 has ∼50% homology with rat MEPE/OF45 (rMEPE/OF45)) in affecting the sens...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833259/ https://www.ncbi.nlm.nih.gov/pubmed/20145617 http://dx.doi.org/10.1038/sj.bjc.6605572 |