NUB1, an interferon-inducible protein, mediates anti-proliferative actions and apoptosis in renal cell carcinoma cells through cell-cycle regulation

BACKGROUND: NEDD8 ultimate buster 1 (NUB1) is an interferon (IFN)-inducible protein that downregulates NEDD8 expression and its conjugation system. Although overexpression of NUB1 induces a growth-inhibitory effect in cells, the mechanisms underlying the anti-mitogenic actions of NUB1 in cancer cell...

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Detalles Bibliográficos
Autores principales: Hosono, T, Tanaka, T, Tanji, K, Nakatani, T, Kamitani, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833260/
https://www.ncbi.nlm.nih.gov/pubmed/20160729
http://dx.doi.org/10.1038/sj.bjc.6605574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833260/
https://www.ncbi.nlm.nih.gov/pubmed/20160729
http://dx.doi.org/10.1038/sj.bjc.6605574

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