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Cell material property dictates stress-induced spreading and differentiation in embryonic stem cells
Growing evidence suggests that physical microenvironments and mechanical stresses, besides soluble factors, help direct mesenchymal stem cell fate. However, biological responses to a local force in embryonic stem (ES) cells remain elusive. Here we show that a local cyclic stress via focal adhesions...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833279/ https://www.ncbi.nlm.nih.gov/pubmed/19838182 http://dx.doi.org/10.1038/nmat2563 |