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Cell material property dictates stress-induced spreading and differentiation in embryonic stem cells

Growing evidence suggests that physical microenvironments and mechanical stresses, besides soluble factors, help direct mesenchymal stem cell fate. However, biological responses to a local force in embryonic stem (ES) cells remain elusive. Here we show that a local cyclic stress via focal adhesions...

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Detalles Bibliográficos
Autores principales: Chowdhury, Farhan, Na, Sungsoo, Li, Dong, Poh, Yeh-Chuin, Tanaka, Tetsuya S., Wang, Fei, Wang, Ning
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833279/
https://www.ncbi.nlm.nih.gov/pubmed/19838182
http://dx.doi.org/10.1038/nmat2563