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Improved Killing of Human High-Grade Glioma Cells by Combining Ionizing Radiation with Oncolytic Parvovirus H-1 Infection

Purpose. To elucidate the influence of ionizing radiation (IR) on the oncolytic activity of Parvovirus H-1 (H-1PV) in human high-grade glioma cells. Methods. Short term cultures of human high-grade gliomas were irradiated at different doses and infected with H-1PV. Cell viability was assessed by det...

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Detalles Bibliográficos
Autores principales: Geletneky, Karsten, Hartkopf, Andreas D., Krempien, Robert, Rommelaere, Jean, Schlehofer, Joerg R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833303/
https://www.ncbi.nlm.nih.gov/pubmed/20224643
http://dx.doi.org/10.1155/2010/350748