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Roles of B cells in rheumatoid arthritis
B lymphocytes play several critical roles in the pathogenesis of rheumatoid arthritis. They are the source of the rheumatoid factors and anticitrullinated protein antibodies, which contribute to immune complex formation and complement activation in the joints. B cells are also very efficient antigen...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833442/ https://www.ncbi.nlm.nih.gov/pubmed/15180890 http://dx.doi.org/10.1186/ar1010 |