Rapid behavior—based identification of neuroactive small molecules in the zebrafish

Neuroactive small molecules are indispensable tools for treating mental illnesses and dissecting nervous system function. However, it has been difficult to discover novel neuroactive drugs. Here, we describe a high—throughput (HT) behavior—based approach to neuroactive small molecule discovery in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kokel, David, Bryan, Jennifer, Laggner, Christian, White, Rick, Cheung, Chung Yan J., Mateus, Rita, Healey, David, Kim, Sonia, Werdich, Andreas A., Haggarty, Stephen J., MacRae, Calum A., Shoichet, Brian, Peterson, Randall T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834185/
https://www.ncbi.nlm.nih.gov/pubmed/20081854
http://dx.doi.org/10.1038/nchembio.307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834185/
https://www.ncbi.nlm.nih.gov/pubmed/20081854
http://dx.doi.org/10.1038/nchembio.307

Ejemplares similares