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An Essential Role for XBP-1 in Host Protection against Immune Activation in C. elegans
The detection and compensatory response to the accumulation of unfolded proteins in the endoplasmic reticulum (ER), termed the Unfolded Protein Response (UPR), represents a conserved cellular homeostatic mechanism with important roles in normal development and in the pathogenesis of disease1. The IR...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834299/ https://www.ncbi.nlm.nih.gov/pubmed/20182512 http://dx.doi.org/10.1038/nature08762 |