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Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis

Depression has been associated with reduced expression of brain-derived neurotrophic factor (BDNF) in the hippocampus. In addition, animal studies suggest an association between reduced hippocampal neurogenesis and depressive-like behavior. These associations were predominantly established based on...

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Detalles Bibliográficos
Autores principales: Taliaz, D, Stall, N, Dar, D E, Zangen, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834321/
https://www.ncbi.nlm.nih.gov/pubmed/19621014
http://dx.doi.org/10.1038/mp.2009.67